Pre-screening Safety Assessment

90.75 incl. VAT

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We offer a specialized toxicological pre-screening service performed by experienced safety evaluators. This service is designed to evaluate cosmetic formulations prior to laboratory testing. Our safety assessors review the formulation using available toxicological data to ensure that all ingredients and their concentrations are within safe limits. An important part of this assessment is reviewing safety margins (MoS), which help determine whether the formulation poses a risk to consumer health based on ingredient composition.

Understanding MoS values and their importance

The Margin of Safety (MoS) value is a critical measure used to assess the safety of ingredients in cosmetic products. It is the ratio of the No Observable Effect Level (NOEL) or Lowest Observed Adverse Effect Level (LOAEL) for a particular ingredient to the estimated exposure level of that ingredient in the finished product. Essentially, the MoS value helps determine how much safer the product is compared to the threshold at which adverse effects may occur. A higher MoS value indicates a greater margin of safety, while a lower value may indicate potential risks, requiring reformulation or further safety analysis.

Thorough safety assessment for consumer protection

Our safety evaluators use MoS values along with other toxicological data, such as skin irritation, sensitization potential and systemic toxicity, to assess the overall safety of a cosmetic formula. This pre-screening process allows us to identify potential risks early in the development process, reducing the likelihood of setbacks later during laboratory testing or regulatory approval. By thoroughly assessing the safety profile of each ingredient and recommending modifications, we ensure that the formulation meets regulatory requirements and does not harm consumers.

Benefits of pre-screening for cosmetic product development

The pre-screening service offers several important benefits. It helps ensure product compliance with strict regulations, such as those in the European Union’s Cosmetics Regulation and REACH directives. By identifying potential safety issues at an early stage, this service helps streamline the product development life cycle, saving both time and resources. It also reduces the likelihood of delays or rejections during regulatory review, making the process more efficient. Ultimately, our toxicological pre-screening service, led by expert safety evaluators, enables cosmetic brands to deliver products that are not only effective, but also safe for consumer use.

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